Radiation levels of isolation rooms used by radio-iodine ablation patients during hospitalization
##plugins.themes.bootstrap3.article.main##
Abstract
The use of RAI-131 in thyroid carcinoma patients presents a special concern on the environmental radiation safety for those who come in contact with the patients especially after discharge from the facility because of excretion of I131 through perspiration, salivation, breathing and urination. Methods & Materials: The present study was conducted at Nuclear Medicine Oncology and Radiotherapy Institute Nawabshah (NORIN) Sindh from 2017 to 2021 with the objective to evaluate contamination hazards by Excretion made by thyroid cancer patients received iodine therapy stayed in isolation room with doses ranging from 80–200 mCi. The areas included corridor, sink, patient bed, and toilet bowl of isolation rooms before admission and after discharge using LAMSE RM-1001 survey meter. The minimum background radiation level measured before patient stay in isolation room was 0.07 μSv/h while the maximum was 0.40 μSv/h and the mean background reading was 0.18 ± 0.072 μSv/h. The maximum dose rate after discharge was observed at toilet bowl with mean of 9.69 ± 1.98 µSv/hr and minimum of 5.0 µSv/hr and maximum value 13.77 µSv/hr. The readings recorded for the sink were: 2.0 μSv/h minimum, 20.0 μSv/h maximum with a mean of 5.55 ± 1.57 μSv/h while those for the patient bed 0.41 μSv/h minimum, 6.92 μSv/h maximum and a mean of 2.83 μSv/h. the least dose rate was found in isolation room corridor (1.53 ± 0.78 μSv/h) with maximum and minimum values 0.28 & 3.20 μSv/h respectively. Radiation is harmful; safety measures must be ensured to minimize radiation exposure to the family members as well as community either during hospitalization or after discharge of RAI-131 patients. The radiation levels from toilet bowls, beds, sinks, and corridor of isolation rooms were well within the acceptable limits and hence, do not pose significant hazard to the public
##plugins.themes.bootstrap3.article.details##
R. N. Ambade et al., “Development of a dry distillation technology for the production of 131 I using medium flux reactor for radiopharmaceutical applications,” J. Radioanal. Nucl. Chem., vol. 303, no. 1, pp. 451–467, 2015, doi: https://doi.org/10.1007/s10967-014-3423-4.
P. Shackett, Nuclear medicine technology: Procedures and quick reference. Philadelphia, Pennsylvania, Amerika: Lippincott Williams & Wilkins, 2019.
H. A. Ziessman, J. P. O’Malley, and J. H. Thrall, Nuclear medicine: the requisites e-book, 4th ed. China: Elsevier Health Sciences, 2013.
M. G. Stabin, “Health concerns related to radiation exposure of the female nuclear medicine patient.,” Environ. Health Perspect., vol. 105, no. 6, pp. 1403–1409, 1997, doi: https://doi.org/10.1289/ehp.97105s61403.
G. S. Pant, “Dosimetric and radiation safety considerations in radioiodine therapy,” Ind J Nucl Med., vol. 20, no. 20, pp. 1–3, 2005, [Online]. Available: https://cir.nii.ac.jp/crid/1570854175815553920.
M. Ahmad, “Scope of nuclear power in Pakistan,” J. Nucl. Energy Sci. Power Gener. Technol., vol. 0, no. 1, pp. 1–11, 2013, doi: http://dx.doi.org/10.4172/2325-9809.S1-001.
M. R. Blevins and R. L. Andersen, “Radiation protection at US nuclear power plants—today and tomorrow,” Health Phys., vol. 100, no. 1, pp. 35–38, 2011, doi: 10.1097/HP.0b013e3181f6590d.
L. R. Coover, E. B. Silberstein, P. J. Kuhn, and M. W. Graves, “Therapeutic 131I in outpatients: a simplified method conforming to the Code of Federal Regulations, title 10, part 35.75,” J. Nucl. Med., vol. 41, no. 11, pp. 1868–1875, 2000, [Online]. Available: https://jnm.snmjournals.org/content/jnumed/41/11/1868.full.pdf.
G. G. Bural, C. M. Laymon, and J. M. Mountz, “Nuclear imaging of a pregnant patient: should we perform nuclear medicine procedures during pregnancy?,” Mol. Imaging Radionucl. Ther., vol. 21, no. 1, pp. 1–5, 2012, doi: 10.4274/Mirt.123.
L. K. Harding, A. Bossuyt, S. Pellet, C. Reiners, J. Talbot, and E. T. G. E. Risks, “Radiation doses to those accompanying nuclear medicine department patients: a waiting room survey,” Eur. J. Nucl. Med., vol. 21, no. 21, pp. 1223–1226, 1994, doi: https://doi.org/10.1007/BF00182357.
W. H. Thomson, N. J. Harding, A. Mills, H. Warren, and L. K. Harding, “Two waiting rooms or one,” Eur J Nucl Med, vol. 15, no. 15, pp. 1–570, 1989.
J. T. Bushberg, J. anthony Seibert, J. Edwin M. Leidholdt, and J. M. Boone, The essential physics of medical imaging, 3rd ed. Philadelphia, Pennsylvania, Amerika: Lippincott Williams & Wilkins, 2011.
G. B. Saha, Physics and radiobiology of nuclear medicine, 4th ed. New York City, USA: Springer Science & Business Media, 2012.
C. Wanke, J. Pinkert, B. Szermerski, and L. Geworski, “Assessment of the radiation exposure of relatives and caregivers of patients treated with Ra-223–Results of a German multicenter study,” Z. Med. Phys., vol. 31, no. 1, pp. 58–64, 2021, doi: https://doi.org/10.1016/j.zemedi.2020.09.002.
D. S. Cooper et al., “Management guidelines for patients with thyroid nodules and differentiated thyroid cancer: The American Thyroid Association Guidelines Taskforce,” Thyroid, vol. 16, no. 2, pp. 109–142, 2006, doi: https://doi.org/10.1089/thy.2006.16.109.
S. Mathur et al., “Emergency imaging in pregnancy and lactation,” Can. Assoc. Radiol. J., vol. 71, no. 3, pp. 396–402, 2020.
M. Blum, S. Tiu, M. Chu, S. Goel, and K. Friedman, “I-131 SPECT/CT elucidates cryptic findings on planar whole-body scans and can reduce needless therapy with I-131 in post-thyroidectomy thyroid cancer patients,” Thyroid Radiol. Nucl. Med., vol. 21, no. 11, pp. 1235–1247, 2011, doi: https://doi.org/10.1089/thy.2011.0010.
O. Kupik et al., “The Effect of Thyroid Hormone Withdrawal, Performed to Evaluate the Success of I-131 Ablation, On Quality of Life in Female Patients With Low-Risk Differentiated Thyroid Cancer,” Res. Sq., vol. 1, no. 23, pp. 1–21, 2021, doi: https://doi.org/10.21203/rs.3.rs-684400/v1.
M. Mulazimoglu, N. Edis, M. O. Tamam, E. Uyanik, and T. Ozpacaci, “The evaluation of the external dose measurement of the patients treated with radioiodine therapy,” Radiat. Prot. Dosimetry, vol. 141, no. 3, pp. 233–238, 2010, doi: https://doi.org/10.1093/rpd/ncq179.
M. Waqar, M. Shahban, Q. Soomro, and M. N. Abro, “Institution-based assessment of cancer patients treated by external beam radiotherapy in the rural area of Sindh, Pakistan: Five years of data analysis,” Middle East J. Cancer, vol. 9, no. 3, pp. 217–222, 2018, doi: https://doi.org/10.30476/mejc.2018.42126.
M. Waqar, M. Shahban, Q. Soomro, and T. A. Afridi, “Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan.,” Pakistan J. Nucl. Med., vol. 12, no. 1, pp. 31–36, 2022, doi: https://doi.org/10.24911/PJNMed.175-1636355717 OPEN.
P. J. Mountford, “Risk assessment of the nuclear medicine patient.,” Br. J. Radiol., vol. 70, no. 835, pp. 671–684, 1997, doi: https://doi.org/10.1259/bjr.70.835.9245878.
J. E. Ejeh, T. H. Abiodun, K. S. Adedapo, Y. A. Onimode, and O. A. Ayeni, “Radiation levels from toilets used by patients injected with 99mTc-based radiopharmaceuticals in Ibadan,” Mol. Imaging Radionucl. Ther., vol. 23, no. 2, p. 60, 2014, doi: 10.4274/mirt.82905.
F. Begum et al., “Radiation exposure levels in close proximity to therapeutic patients treated for thyroid carcinoma with high dose I-131,” Bangladesh J. Nucl. Med., vol. 17, no. 1, pp. 50–54, 2014, doi: https://doi.org/10.3329/bjnm.v17i1.22491.
W. Changmuang et al., “Radiation from an admitted thyroid cancer patient with high dose I-131 treatment in related hospitalized area and exposure to associated personnel in Ramathibodi’s new inpatient unit,” Asean J Radiol, vol. 18, no. 2, pp. 118–122, 2012, [Online]. Available: https://www.researchgate.net/publication/236979011.
E. Ibis, C. R. Wilson, B. D. Collier, G. Akansel, A. T. Isitman, and R. G. Yoss, “Iodine-131 contamination from thyroid cancer patients,” J. Nucl. Med., vol. 33, no. 12, pp. 2110–2115, 1992, [Online]. Available: https://jnm.snmjournals.org/content/jnumed/33/12/2110.full.pdf.
N. H. Mohd Zainudin, J. Mohd Radzi, W. AI, and I. SNI, “Surface contamination in skin and room during hospitalization of thyroid cancer patient receiving radioiodine ablation,” IOSR J. Dent. Med. Sci., vol. 2, no. 1, pp. 27–33, 2012, [Online]. Available: https://core.ac.uk/download/pdf/222964081.pdf.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.